To expand to your the earlier XRCC1 overall performance and you can clarify the fresh role from polymorphisms from inside the DNA fix family genes from inside the kidney disease awareness, we examined multiple single nucleotide polymorphisms (SNPs) regarding the ft excision fix (BER), nucleotide excision repair (NER) and you may double strand split (DSB) fix routes for the a population-established study of 355 kidney cancers cases and you will 559 regulation off The newest Hampshire.

Investigation group

We identified every cases of kidney cancer diagnosed one of The fresh Hampshire citizens, years 25–74 years, out of July 1, 1994 in order to June 30, 1998 regarding County Cancers Registry.